Santee, South Carolina, is more than just a charming lakefront town—it’s a hidden gem for food lovers. With a mix of Southern comfort food, fresh seafood, and barbecue specialties, Santee’s dining scene is sure to impress. Whether you’re visiting for a fishing trip on Lake Marion or just passing through on I-95, these must-try dishes from the town’s top restaurants should be on your list.
1. Clark’s Restaurant & Inn – The Famous Prime Rib
A Timeless Classic for Steak Lovers
If you ask locals about the best place for a hearty meal, Clark’s Restaurant & Inn will likely be their first recommendation. Established in 1946, this restaurant is an institution in Santee, known for its slow-roasted Prime Rib.
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Why It’s a Must-Try:
- The prime rib is aged and slow-roasted for hours, creating a tender and flavorful cut of beef.
- It’s served with au jus and creamy horseradish sauce, adding an extra layer of flavor.
- You can order it in different sizes, but the King Cut (16 oz.) is the top choice for steak lovers.
Other Favorites: If prime rib isn’t your thing, Clark’s also serves fresh seafood platters and grilled pork chops that get rave reviews.
2. Sweatman’s BBQ – Whole Hog Barbecue
A True Taste of South Carolina Barbecue
Located in nearby Holly Hill, Sweatman’s BBQ is a family-owned establishment renowned for its authentic whole hog barbecue. Operating since the 1970s, this restaurant has become a staple for barbecue enthusiasts seeking genuine South Carolina flavors.
Why It’s a Must-Try:
- Whole Hog Tradition: Sweatman’s specializes in cooking whole hogs over oak and hickory coals, ensuring a rich and smoky flavor in every bite.
- Mustard-Based Sauce: Their signature mustard-based barbecue sauce, a South Carolina classic, adds a tangy zest that complements the tender pork perfectly.
- Homemade Sides: Pair your barbecue with traditional sides like coleslaw, baked beans, and cornbread, all made from scratch.
Other Favorites: Don’t miss their crispy fried chicken and the unique experience of their buffet-style serving, allowing you to sample a variety of Southern delicacies.
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3. Captain’s Quarters – Fresh Fried Catfish
A Seafood Lover’s Dream
Lake Marion is known for its abundant catfish population, and no trip to Santee is complete without trying some local seafood. Captain’s Quarters is the go-to spot for freshly fried catfish.
Why It’s a Must-Try:
- The catfish is caught fresh from Lake Marion, making it one of the freshest seafood options in town.
- It’s seasoned and fried to perfection, creating a crispy outside and a flaky, tender inside.
- It comes with homemade tartar sauce and hush puppies, adding a perfect balance of flavors.
Other Favorites: Their grilled shrimp and crab cakes are also popular choices.
4. Thai House II – Spicy Basil Chicken
A Taste of International Flavor
For those craving something different, Thai House II brings authentic Thai cuisine to Santee. Located right off I-95, it’s a favorite among travelers and locals alike.
Why It’s a Must-Try:
- Their Spicy Basil Chicken is a customer favorite, offering a mix of savory, spicy, and aromatic Thai flavors.
- It’s cooked with fresh basil, chili peppers, garlic, and onions, giving it an authentic taste.
- You can adjust the spice level to your preference—from mild to extra hot.
Other Favorites: Their Pad Thai and Tom Yum Soup are also must-try dishes.
5. The Lakehouse – Shrimp & Grits
Southern Comfort with a View
Located right by Lake Marion, The Lakehouse is a popular dining destination known for its fresh seafood, steaks, and classic Southern dishes. Whether you’re dining inside or enjoying the view from their outdoor seating, the atmosphere here is as good as the food.
Why It’s a Must-Try:
- Their Shrimp & Grits is a Lowcountry classic, featuring fresh local shrimp, creamy stone-ground grits, and a rich, flavorful sauce.
- The dish is seasoned with Cajun spices and often topped with andouille sausage, adding a smoky, spicy kick.
- It’s a Southern staple, perfect for brunch, lunch, or dinner.
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Other Favorites: The ribeye steak, seafood pasta, and crab-stuffed flounder are also highly recommended.
Final Thoughts: Where to Eat in Santee?
Santee’s food scene is diverse, offering everything from mouthwatering barbecue and fresh seafood to authentic Thai flavors and Southern comfort classics. No matter what you’re craving, these must-try dishes represent the best of what Santee’s restaurants have to offer.
Next time you find yourself in town, be sure to stop by one of these top spots and experience the local flavors that make Santee a hidden gem for food lovers!
No matter which dish you try, you’re in for a true taste of Southern hospitality and local flavor in Santee!